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  • 贾英民,刘杨柳,陈洲.抗菌肽研究现状及其在食品安全中的应用前景[J].食品科学技术学报,2017,35(6):1-9.    [点击复制]
  • JIA Yingmin,LIU Yangliu,CHEN Zhou.Research Status and Application Prospect in Food Safety of Antimicrobial Peptides[J].Journal of Food Science and Technology,2017,35(6):1-9.   [点击复制]
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抗菌肽研究现状及其在食品安全中的应用前景
贾英民,刘杨柳,陈洲
0
(北京工商大学 食品学院, 北京 100048)
摘要:
针对微生物污染引起的食品安全与耐药菌株引起的环境安全等问题,广谱、高效的新型天然食品防腐剂的开发应用已成为现代食品安全的重要研究趋势。抗菌肽(antimicrobial peptides,AMPs)由于其抑菌谱广、稳定性好,抑菌机制独特、不易残留等优势而备受关注。随着研究的不断深入,AMPs将有望在食品安全的应用中发挥关键性作用。有鉴于此,对近年来国内外抗菌肽(AMPs)的相关研究进行了总结,综述了AMPs资源挖掘、分类情况以及细菌、真菌、寄生虫、病毒、肿瘤细胞的生物抗性、作用机制的研究进展;同时,对AMPs在食品安全中的潜在应用方向、亟待解决的科学问题进行了分析,并提供相应的解决策略,供本领域的研究者参考。
关键词:  抗菌肽  食品安全  研究现状  应用前景
DOI:10.3969/j.issn.2095-6002.2017.06.001
投稿时间:2017-11-02
基金项目:国家自然科学基金资助项目(31771951)。
Research Status and Application Prospect in Food Safety of Antimicrobial Peptides
JIA Yingmin,LIU Yangliu,CHEN Zhou
(School of Food Science and Technology,Beijing Technology and Business University,Beijing 100048,China)
Abstract:
For problems of food safety caused by microbial contamination and environmental safety due to drug-resistant strains, the development of emerging natural food additives with broad-spectrum and high-efficiency has been vital study trends in a modern food safety. Antimicrobial peptides(AMPs) are paid much attention for its advantage of broad-spectrum, good stability, unique antimicrobial mechanism of action and lower residue. With the further research, AMPs are expected to play a vital role in the application of food safety. Considering it, AMPs-related researches abroad were concluded in recent years. A review of the exploring and classification situation of AMPs,the development of bio-resistance and mechanism for bacteria, fungi, parasites, virus and tumor cells was provided. Meanwhile, the potential application fields of AMPs in food safety and scientific problems urgent to solve were analyzed. The resolution strategy also is provided for researchers as a reference in the field.
Key words:  antimicrobial peptides  food safety  research status  application prospect